Khuda Kasam is the story of the fight of a brave truck driver Hussain and an honest CBI officer Neetu Singh against a corrupt politician, Bhawani Prasad Lalla who murders the chief minister. CBI Officer Neetu Singh is sent to investigate the murder and she finds the evidence against BPL but he uses Lakhan Singh and Wagmare who are high ranking police officers to manipulate the evidence and Neetu Singh is sent to jail.
Hussain has also suffered in the hands of BPL as he worked for him but was sent to jail on false charges. He wants revenge but his mother makes him promise that he will not fight. The promise is broken when handicapped Shanti Devi is kidnapped by BPL as she is Neetu Singh’s mother.
Neetu Singh also leaves jail and disguises as a pop star and BPL falls in love with her and makes Lakhan Singh and Waghmare his enemies. BPL finds out she is Neetu Singh but its too late as Lakhan Singh has no become a witness against BPL. He tries to kill Neetu Singh but Hussain foils all the plans.